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Also indexed as: Mifeprex, RU486


Mifepristone, also known as RU486, is used to induce abortion, and is classified both as a progesterone and a glucocorticosteroid receptor antagonist. It has also been used experimentally to treat Cushing’s syndrome (hyperfunctioning adrenal glands), breast cancer, and glaucoma.

Summary of Interactions with Vitamins, Herbs, and Foods
In some cases, an herb or supplement may appear in more than one category, which may seem contradictory. For clarification, read the full article for details about the summarized interactions.

Beneficial May Be Beneficial: Side effect reduction/prevention—Taking these supplements may help reduce the likelihood and/or severity of a potential side effect caused by the medication.

Modified Shenghua Tang

Depletion or interference

None known

Supportive interaction

None known

Reduced drug absorption/bioavailability

None known

Adverse interaction

None known

An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.

Interactions with Herbs

Modified Shenghua Tang
The most common side effect of mifepristone is excess vaginal bleeding. One controlled study showed that drinking modified shenghua tang (a tea made from bupleurum, angelica, ligusticum, peach kernel, baked ginger, and leonurus) greatly reduced the number of days that bleeding occurred following mifepristone therapy.1


1. Sun L, Pan J. Treating colporrhagia after medical abortion with modified shenghua tang. J Tradit Chin Med 1996;16:263–6.

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