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Also indexed as: Spectazole


Econazole is an antifungal cream used for topical (direct application to the skin) treatment of fungal skin infections. It is used most commonly to treat athlete’s foot (fungal infection of the skin between the toes), jock itch (fungal infection of the skin in the groin region), and ringworm (fungal infection of nonhairy skin), and for external Candida infections. Econazole is for external use only.

Summary of Interactions with Vitamins, Herbs, and Foods
In some cases, an herb or supplement may appear in more than one category, which may seem contradictory. For clarification, read the full article for details about the summarized interactions.

Beneficial May Be Beneficial: Supportive interaction—Taking these supplements may support or otherwise help your medication work better.


Depletion or interference

None known

Side effect reduction/prevention

None known

Reduced drug absorption/bioavailability

None known

Adverse interaction

None known

An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.

Interactions with Herbs

Echinacea (Echinacea purpurea, Echinacea angustifolia)
The combination of oral echinacea with a topical econazole nitrate cream reduced the recurrence of vaginal yeast infections in women compared to those using the cream alone.1


1. Coeugniet EG, Kuhnast R. Recurrent candidiasis: Adjuvant immunotherapy with different formulations of Echinacin. Therapiewoche 1986;36:3352–8.

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