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Also indexed as: Estraval-PA, Estrone, Natural Estrogenic Substance, Ogen, Ortho-Est, Primestrin


Estropipate is used both to treat moderate to severe symptoms associated with menopause, including hot flashes and vaginal dryness, and to prevent osteoporosis. It is in a class of drugs known as estrogens.

There are currently no reported nutrient or herb interactions specifically involving estropipate; however, since it is an estrogen, estropipate might interact with similar compounds. For more information, refer to the estrogen section.

Summary of Interactions with Vitamins, Herbs, and Foods
In some cases, an herb or supplement may appear in more than one category, which may seem contradictory. For clarification, read the full article for details about the summarized interactions.

Depletion or interference

None known

Side effect reduction/prevention

None known

Supportive interaction

None known

Reduced drug absorption/bioavailability

None known

Adverse interaction

None known

An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.

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