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Oxycodone

Also indexed as: M-Oxy, OxyContin, OxyFast, OxyIR, Percolone, Roxicodone

Combination drugs: Endocet, Percocet, Percodan, Roxicet, Roxiprin

Illustration

Oxycodone is a narcotic analgesic used to relieve moderate to severe pain. Oxycodone is available in combination products.

Summary of Interactions with Vitamins, Herbs, and Foods
In some cases, an herb or supplement may appear in more than one category, which may seem contradictory. For clarification, read the full article for details about the summarized interactions.

Depletion or interference

None known

Side effect reduction/prevention

None known

Supportive interaction

None known

Reduced drug absorption/bioavailability

None known

Adverse interaction

None known

An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.

Interactions with Foods and Other Compounds

Food
Oxycodone may cause gastrointestinal (GI) upset. Oxycodone-containing products may be taken with food to reduce or prevent GI upset.1 A common side effect of narcotic analgesics is constipation.2 Increasing dietary fiber (especially vegetables and whole-grain foods) and water intake can ease constipation.

Alcohol
Oxycodone may cause drowsiness, dizziness, or blurred vision. Alcohol may intensify these effects and increase the risk of accidental injury.3 To prevent problems, people taking oxycodone should avoid alcohol.

References:

1. Threlkeld DS, ed. Central Nervous System Drugs, Narcotic Agonist Analgesics. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, Feb 1990, 242–3v.

2. Threlkeld DS, ed. Central Nervous System Drugs, Narcotic Agonist Analgesics. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, Feb 1990, 242–3v.

3. Threlkeld DS, ed. Central Nervous System Drugs, Narcotic Agonist Analgesics. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, Feb 1990, 242–3v.

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