Also indexed as: Pentoxil, Trental
Pentoxifylline decreases blood thickness and improves red blood cell flexibility.
Pentoxifylline is used to improve symptoms of
intermittent claudication and in the treatment of other circulatory disorders.
Summary of
Interactions with Vitamins, Herbs, and Foods
In some cases, an herb or supplement may appear in more than one category, which may seem
contradictory. For clarification, read the full article for details about the summarized
interactions.
 May Be Beneficial: Supportive
interaction—Taking these supplements may support or otherwise help your medication
work better. |
Vitamin E
|
| Depletion or interference |
None known
|
| Side effect reduction/prevention |
None known
|
| Reduced drug
absorption/bioavailability |
None known
|
| Adverse interaction |
None known
|
An asterisk (*) next to an item in the summary indicates that the
interaction is supported only by weak, fragmentary, and/or contradictory scientific
evidence.
Interactions with Dietary Supplements
Vitamin
E
The combination of vitamin E and pentoxifylline has been used successfully to reduce damage to
normal tissues caused by radiation therapy.1
Interactions with Foods and Other Compounds
Food
Pentoxifylline should be taken with meals.2
References:1. Delanian S, Balla-Mekias S, Lefaix JL. Striking regression of chronic
radiotherapy damage in a clinical trial of combined pentoxifylline and tocopherol. J Clin
Oncol 1999;17:3283–90.
2. Threlkeld DS, ed. Blood Modifiers, Hemorheologic Agent,
Pentoxifylline. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and
Comparisons, Mar 1997, 89f–9g.